FAQ

Psilocybin is a naturally occurring psychedelic compound produced by certain species of mushrooms. It is present throughout the organism, in the fruiting body, the truffle (sclerotium), and the mycelium. Once ingested, the body converts psilocybin into psilocin, a molecule that interacts with serotonin receptors and temporarily alters perception and cognition. This mechanism is currently being investigated for its potential in treating conditions such as depression and post-traumatic stress disorder (PTSD).

In psilocybin-producing fungi, all anatomical parts contain the same active compound. The truffle, a compact underground nutrient reserve, forms when the mushroom enters a protective state in response to environmental stress. In the Netherlands, where truffles remain legal, we are able to offer them because they contain a slightly milder concentration of psilocybin and are associated with fewer adverse reactions. Read our full guide to magic truffles for more detail.

Available research, including reports from the Drug Policy Alliance, indicates that psilocybin does not cause dependency. The body quickly develops tolerance, meaning repeated use diminishes its effects, reducing the risk of compulsive consumption. Interestingly, several studies now examine whether psilocybin could help address certain forms of addiction.

Beyond the intended alteration of perception, side effects are generally limited. Some individuals may experience nausea, dizziness, temporary anxiety, or an increase in heart rate. In rare cases, users report numbness, tremors, or paranoid thoughts. For people without underlying psychiatric vulnerabilities, these reactions usually resolve on their own.

For safety reasons, psilocybin is not recommended for individuals with:

• A diagnosed psychiatric condition such as schizophrenia, bipolar disorder, or borderline personality disorder
• A close family history of these conditions
• Ongoing treatment with antidepressants, neuroleptics, or other medications affecting serotonin (medical advice is essential)
• Pregnancy or breastfeeding

Please review the full list of contraindications before applying to a retreat.

Driving is strictly discouraged until the effects have completely worn off. As with any psychoactive substance, including legal medications, reaction time, coordination, and sensory perception can be impaired. Most people are safe to drive only once the body has fully metabolised the compound, typically 12 to 16 hours later.

Growing evidence suggests that psilocybin may alleviate symptoms of depression, particularly when traditional treatments have been ineffective. However, it is important to note that Retraite Eveil does not offer medical or psychiatric treatment. Our retreats are wellness-oriented and do not substitute for clinical therapy.

Some medications interact poorly with psilocybin, particularly neuroleptics and antidepressants, as they influence similar neurological pathways. Anyone who has used these treatments within the last three years should speak with a qualified medical professional before considering a psychedelic experience. Certain antidepressants increase serotonin availability, and although rare, excessive serotonin levels may lead to serotonin syndrome. Similarly, individuals undergoing treatment for high blood pressure or kidney problems should refrain from consuming psychoactive substances. See our contraindications page for a full breakdown by medication class.

We apply a strict screening process and decline applications when a participant's health could present a risk to themselves or others. During the retreat, an experienced team remains on-site to provide reassurance, manage anxiety or difficult moments, and intervene if any unsafe behaviour arises. The retreat centre is also located approximately 25 minutes from the nearest hospital for additional security. Learn more about the people behind this care on our team page.

If you reside in a country where psychedelic mushrooms or truffles are illegal, you cannot transport them. Possession and consumption remain prohibited in most jurisdictions. Regardless of where you live, Retraite Eveil does not provide truffles to take away. We believe they should be consumed only in a calm, supportive environment under professional supervision.